Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’

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چکیده

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Natural solution to antibiotic resistance: bacteriophages ‘The Living Drugs’

Antibiotics have been a panacea in animal husbandry as well as in human therapy for decades. The huge amount of antibiotics used to induce the growth and protect the health of farm animals has lead to the evolution of bacteria that are resistant to the drug's effects. Today, many researchers are working with bacteriophages (phages) as an alternative to antibiotics in the control of pathogens fo...

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Antibiotic therapy represents one of the most important medical advances of the 20th century and is a valuable resource in combating infectious diseases. Its therapeutic use, however, has been associated with the emergence of antibiotic-resistant bacteria. There are many naturally occurring ways in which susceptible bacteria become resistant to antibiotics, including by chromosomal mutations an...

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Potential impact of environmental bacteriophages in spreading antibiotic resistance genes.

The idea that bacteriophage transduction plays a role in the horizontal transfer of antibiotic resistance genes is gaining momentum. Such transduction might be vital in horizontal transfer from environmental to human body-associated biomes and here we review many lines of evidence supporting this notion. It is well accepted that bacteriophages are the most abundant entities in most environments...

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Could bacteriophages transfer antibiotic resistance genes from environmental bacteria to human-body associated bacterial populations?

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ژورنال

عنوان ژورنال: World Journal of Microbiology and Biotechnology

سال: 2014

ISSN: 0959-3993,1573-0972

DOI: 10.1007/s11274-014-1655-7